Dimethyl Isosorbide is a non-ionic solvent that is highly miscible with most surfactants, co-solvents, colorants, and peptides. DMI is soluble in many ingredients including water, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20, and polysorbate 80; It is insoluble in hydrogenated castor oil, lanolin, mineral oils or silicone oil. It is FDA approved up to 15% in topical over-the-counter products.
Dimethyl Isosorbide is used in various pharmaceutical applications, mainly creams, lotions, and sprays applied to the skin. It is used to stabilize, solvate, and deliver active ingredients into the skin for significantly better penetration and performance. The most common products include anti-acne, ant-aging, self-tanning, and topical ointments.
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Also Known As
DMI; 2,5-dimethylisosorbide; Isosorbide dimethyl ether